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Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
专利权人:
Signal Pharmaceuticals; LLC
发明人:
Steven Clareen,Veronique Plantevin-Krenitsky,Moorthy Palanki,Yoshitaka Satoh
申请号:
US14918655
公开号:
US09725450B2
申请日:
2015.10.21
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein are Aminopurine Compounds having the following structure:wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
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