Indiana University Research and Technology Corporation
发明人:
Zhong-Yin Zhang,Sheng Zhang
申请号：
US14975232
公开号：
US10072043B2
申请日:
2015.12.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
