Methods of Blocking the CXCR-4/SDF-1 Signaling Pathway With Inhibitors of Brutons Tyrosine Kinase

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专利权人:

发明人:

Raquel Izumi,Francisco Salva,Ahmed Hamdy

申请号：

US15917191

公开号：

US20180193337A1

申请日:

2018.03.09

申请国别(地区):

US

年份:

2018

代理人:

摘要：

In some embodiments, the present invention relates to novel small molecule inhibitors that block the CXCR4-SDF-1 signaling pathway by directly inhibiting the members of the Tec family of kinases, namely Broncs tyrosine kinese (BTK) and their use in treating disorders in which pathogenesis is mediated by the CXCR4-SDF-1 signaling pathway.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/