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NEW BENZIMIDAZOLES DERIVATIVES AS TEC KINASES FAMILY INHIBITORS
专利权人:
发明人:
Alain Laurent,Yannick Rose,Stephen J. Morris
申请号:
US15772919
公开号:
US20180319781A1
申请日:
2016.09.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a novel family of covalent kinases inhibitors. Compounds of this class have been found to have inhibitory activity against members of the Tec kinase family, particularly ITK, BTK, BMX, Tec and/or RLK. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvate of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof and its use in therapy.
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