晶形农业专利-农业专业知识服务系统

发明人:: BOSS, CHRISTOPH,博斯　克里斯多夫,BROTSCHI, CHRISTINE,布洛奇　克利斯汀,GUDE, MARKUS,古德　马库斯,古德　馬庫斯,HEIDMANN, BIBIA,海曼　毕比雅,海曼　畢比雅,SIFFERLEN, THIERRY,席佛林　赛瑞,席佛林　賽瑞,VON RAUMER, MARKUS,凡　奥莫　马库斯,凡　奧莫　馬庫斯,W,博斯克里斯多夫,布洛奇克利斯汀,古德马库斯,古德馬庫斯,海曼毕比雅,海曼畢比雅,席佛林赛瑞,席佛林賽瑞,凡奥莫马库斯,凡奧莫馬庫斯

摘要：: The invention relates to crystalline forms of (S)-(2-(6-chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone, processes for the preparation thereof, pharmaceutical compositions containing such crystalline forms, pharmaceutical compositions prepared from such crystalline forms, and their use as a medicament, especially as orexin receptor antagonists.本發明係關於(S)-(2-(6-氯-7-甲基-1H-苯并[d]咪唑-2-基)-2-甲基吡咯啶-1-基)(5-甲氧基-2-(2H-1,2,3-三唑-2-基)苯基)甲酮之晶形、其製備方法、含有該等晶形之醫藥組合物、自該等晶形製備之醫藥組合物，及其作為藥劑、尤其作為食慾素受體拮抗劑之用途。