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SUBSTITUTED BENZTROPINE ANALOGS FOR TREATMENT OF DEMENTIA
专利权人:
发明人:
Somasundar Prasad Gabbita,Frank Paul Zemlan
申请号:
US14724253
公开号:
US20150258077A1
申请日:
2015.05.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method for treating a condition selected from Alzheimers disease, mild cognitive impairment, age-associated dementia, and frontotemporal dementia, comprises administering to a patient in need of such treatment a safe and effective amount of a compound having the formula:wherein R is selected from hydrogen, alkyl, alkoxy, arylalkyl, aryloxyalkyl, cinnamyl and acyl and R1 and R2 are independently selected from hydrogen, alkyl, alkoxy, hydroxy, halogen, cyano, amino and nitro with the proviso that if R is methyl, R1 and R2 are not both hydrogen and the compound comprises pharmaceutically acceptable salts thereof.
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