Rina Rosin-Arbesfeld,Ella Sklan,Alona Zilberberg,Naama David
申请号:
US13145332
公开号:
US20120065251A1
申请日:
2010.01.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides a nucleic acid construct comprising a promoter sequence derived from microRNA-21 (miR-21) linked to a nucleic acid sequence encoding an anti-cancer agent, an example of which is a toxin. The constructs of the invention are particularly useful for treating tumors expressing miR-21.