A navigation system for minimally invasive operation comprises: a pre-operative data module (100) for acquiring a 3D model of the human body； an intra-operative data module (200) for acquiring a pose code, and looking up a corresponding pre-operative time according to the pose code； a positioning module (300) for acquiring position data of operative instrument and human body positioners (301, 201, 302)； a navigation module (400) for receiving the 3D model of the human body and the position data of the operative instrument and human body positioners (301, 201, 302), acquiring a model of the operative instrument according to the position data of the operative instrument positioner (301), and displaying the model of the operative instrument and the 3D model of the human body on the basis of the position data of the human body positioners (201, 302) using an augmented reality display device； an intra-operative imaging module (500) for acquiring imaging data of a surgical site when abnormity occurs； and the navigation module (400) for adjusting the 3D model of the human body according to the imaging data. The solution can effectively superimpose a fixed model generated prior to the operation upon the body parts moves with natural respiration in real time during the operation and display the result, thus solving the problem in which the minimally invasive operation is affected by abnormal human respiration during the operation.La présente invention concerne un système de navigation pour une opération à effraction minimale qui comprend : un module (100) de données préopératoires permettant d'acquérir un modèle 3D du corps humain ； un module (200) de données peropératoires permettant d'acquérir un code de pose, et de rechercher une durée préopératoire correspondante en fonction du code de pose ； un module de positionnement (300) permettant d'acquérir des données de position de l'instrument opératoire et des positionneurs (301, 201, 302) du corps humain ； un module de naviga
