Pharmaceutical composition for preventing or treating of cirrhosis of liver comprising G protein coupled receptor 119 ligand as an active ingredient

• 收藏
• 分享

专利权人:

发明人:

Keon Wook KANG,Kyeong LEE,Jin Won YANG

申请号：

US15355376

公开号：

US20170143714A1

申请日:

2016.11.18

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Provided is a pharmaceutical composition for preventing or treating liver fibrosis, comprising a GPR119 ligand as an active ingredient. The composition comprising the GPR119 ligand as an active ingredient significantly inhibits the expression of collagen I, transforming growth factor β (TGFβ) and α-smooth muscle actin (α-SMA), thereby inhibiting HSC activation, and also significantly inhibits HSC proliferation. Therefore, the composition may be effectively applied in improvement, prevention, inhibition or treatment of liver fibrosis

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/