Ayman M. Atta,Hamad A. Al-Lohedan,Abdelrahman O. Ezzat
申请号:
US15378017
公开号:
US09828445B1
申请日:
2016.12.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Synthesis of modified chitosan particles for oral insulin delivery includes amidation of chitosan with a fatty acid, a modified fatty acid, and/or an amino acid. The amidated chitosan can be grafted with N-isopropylacrylamide (NIPAm) and cross-linked to provide the modified chitosan particles.