National Institute Of Advanced Industrial
Science and Technology;University of Tsukuba
发明人:
申请号:
EP20852409.0
公开号:
EP4042862A1
申请日:
2020.08.07
申请国别(地区):
EP
年份:
2022
代理人:
摘要:
An artificial gene has a 15N abundance exceeding a natural abundance in bases of at least a portion of DNA. A method for mutating a gene includes a first step of producing a state in which 15N is unevenly distributed into a prescribed DNA in a living cell; and a second step of irradiation with a proton beam at an energy at which the 15N produces a resonant nuclear reaction.