A sulfonamide derivative represented by the following general formula (1) or a pharmaceutically acceptable salt thereof: ** Formula ** wherein A represents a group represented by the following general formula (2-1), (2-2), or (2-3), ** Formula **, wherein The arm is a cyclic alkyl or aromatic ring group containing 0, 1, 2, 3, or 4 heteroatoms that are selected from oxygen atoms, sulfur atoms, and nitrogen atoms, each of R1, R11, and R21 independently represents any of a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, an alkoxy group lower, a lower alkylthio group, a lower hydroxyalkyl group, a lower hydroxyalkenyl group, a lower hydroxyalkoxy group, a lower halogenoalkyl group, a lower halogenoalkoxy group, a lower halogenoalkylthio group, a lower halogenoalkenyl group, a nitro group, a gru po cyano, an amino group, a lower alkylamino group, a group (lower alkylamino) lower alkyl, a carboxyl group, a lower alkyloxycarbonyl group, a carbamoyl group, a lower alkanoyl group, an aroyl group, a lower aquylsulfonyl group, a group sulfamoyl, and an ammonium group, each of R12, R13, and R14 independently represents any of a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a lower alkoxy group, a lower alkylthio group, a lower hydroxyalkyl group, a lower hydroxyalkenyl group, a lower hydroxyalkoxy group, a lower halogenoalkyl group, a lower halogenoalkoxy group, a lower halogenoalkylthio group, a lower halogenoalkenyl group, a nitro group, a group cyano, an amino group, a lower alkylamino group, a lower alkyl alkylamino group, a carboxyl group, an alkyloxy group lower carbonyl, a carbamoyl group, a lower alkanoyl group, an aroyl group, a lower aquylsulfonyl group, a sulfamoyl group, and an ammonium group, each of R2, R3, R22, R23, R24, and R25 independently represents any one of a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl