1. A compound of formula I wherein R is selected from the group consisting of i) aryl and ii) heteroaryl, R is selected from the group consisting of i) H, ii) Ci-alkyl and iii) -N (R, R) R is selected from the group consisting of i) And R and R together with the nitrogen to which they are attached form a five-membered heterocyclyl, optionally substituted Z, or 3-aza-bicyclo [ [3.2.1] octan-3-yl optionally substituted with C-alkyl R is selected from the group consisting of i) H and ii) C-alkyl R 1 is -SO-C alkyl n is 0, 1 or 2 m is 0, 1 or 2 A is independent. is selected from the group consisting of i) acetamidyl, ii) acetyl, iii) amido, iv) amino, v) C-alkoxy, vi) C-alkyl, vii) carboxy, viii) cyano, ix) halogen, x) Ci-alkoxy, xi) halo-Ci-alkyl, xii) hydroxy, xiii) -N (Ci-alkyl, Ci-alkyl) and xiv) -N (H, Ci-alkyl), xv) -SO-C-alkyl, is C-alkyl Z is independently selected from the group consisting of i) aryl optionally substituted with 1 or 2 substituents independently selected from acetamidyl, acetyl, amido, amino, carboxy, cyano, halo, halogen-C-alkoxy, halogen-C-alkyl, hydroxy, (C-alkyl, H) N-, (C-alkyl, C-alkyl) N-, C-alkyl-S (O) -, C-alkoxy, C-alkyl and nitro, ii) heteroaryl optionally substituted with 1 or 2 C-alkyl, iii) cycloalkyl optionally substituted with 1 or 2 substituents independently selected from acetamidyl, acetyl, amido, amino, carboxy, cyano, halogen, halo-C alkoxy and, halogen-C-alkyl, hydroxy, (C-alkyl, H) N-, (C-alkyl, C-alkyl) N-, C-alkyl-S (O) -, C-alkoxy, C-alkyl and nitro, iv) acetyl, v) benzoyl optionally substituted with 1 or 2 substituents independently selected from acetamidyl, acetyl, amido, amino, carboxy, cyano, halo,
