THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;加利福尼亞大學董事會
发明人:
ZHANG, Liangfang,PANG, Zhiqing,FANG, Ronnie H.,HU, Che-Ming Jack,FANG, Ronnie H.,方弘博,HU, Che-Ming Jack,胡哲銘
申请号：
HK18104599.7
公开号：
HK1245109A
申请日:
2018.04.09
申请国别(地区):
HK
年份:
2018
代理人:
摘要：
The present invention relates treatments of a toxin in a subject. The toxin at least partially effects its toxicity in the subject via binding to a target cell of the subject. The present invention provides for methods, combinations and pharmaceutical compositions for decreasing or neutralizing the effect of a toxin in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, and an outer surface comprising a cellular membrane derived from a source cell. Exemplary toxins include acetylcholinesterase (AChE) inhibitors such as organophosphate poisoning.
