Liangfang Zhang,Zhiqing Pang,Ronnie H. Fang,Che-Ming Jack Hu
申请号：
US15568316
公开号：
US20180140558A1
申请日:
2016.04.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates treatments of a toxin in a subject. The toxin at least partially effects its toxicity in the subject via binding to a target cell of the subject. The present invention provides for methods, combinations and pharmaceutical compositions for decreasing or neutralizing the effect of a toxin in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, and an outer surface comprising a cellular membrane derived from a source cell. Exemplary toxins include acetylcholinesterase (AChE) inhibitors such as organophosphate poisoning.
