The present invention relates to an extract from mangosteen (Garcinia mangostana) fruit and a use thereof. The mangosteen fruit extract is obtained by water or ethanol from a whole fruit or a pericarp of mangosteen. The mangosteen fruit extract has activities of inhibiting hyaluronidase and DNA repair, so that it can be included as an effective ingredient in a composition having activities of inhibiting hyaluronidase and DNA repair.本發明係有關於一種山竹(Garcinia mangostana)果萃取物及其用途。此山竹果萃取物係以水或乙醇萃取山竹全果或山竹果殼所獲得，具有抑制透明質酸酶活性及DNA修復的活性，可作為具有抑制透明質酸酶活性及DNA修復的活性之組成物的有效成分。
