A protection cover for a nose endoscopy, and more particularly to a protection cover for a nose endoscopy that can prevent discharges generated during sneezing in a nose endoscopy from being ejected to a healthcare provider. The protection cover for a nose endoscopy includes: a fixed member coupled to the head of a wearer; and a main cover coupled to a lower portion of the fixed member and configured to cover a front surface of the face of the wearer, A through-hole for exposing the nostrils of the wearer to the outside is formed in the main cover.