Qiang Yang,Beth Lorsbach,Xiaoyong Li,Gary Roth,David E. Podhorez
申请号:
US14517315
公开号:
US09249122B1
申请日:
2014.10.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
3-(3-Chloro-1H-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine•dihydrochloride with acrylonitrile to provide 1-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-amine, by oxidizing to provide 3-(3-amino-1H-pyrazol-1-yl)pyridine, and by converting the amino group to a chloro group by a Sandmeyer reaction.