PROBLEM TO BE SOLVED: To provide a method for producing a transdermal absorption sheet capable of suppressing entrainment of air bubbles in a liquid material. A method for manufacturing a percutaneous absorption sheet includes a step of preparing a mold 120 having a plurality of needle-shaped recesses and a step portion surrounding the needle-shaped recesses and having a step portion higher than a surface where the needle-shaped recesses are formed； And a step of supplying the liquid material 170 for the transdermal absorption sheet to a region surrounded by the stepped portion of the mold from the discharge opening, and the filling head has a head main body 152 having an inner wall surface defining a supply conduit. And the inner wall surface includes a tapered conduit surface 160B that defines a tapered conduit that gradually increases in diameter toward the ejection opening of the head body. [Selection diagram] FIG.【課題】液状材料への気泡の巻き込みを抑制することができる経皮吸収シートの製造方法を提供する。【解決手段】経皮吸収シートの製造方法は、複数の針状凹部、及び複数の針状凹部を囲み、針状凹部形成面より高い段差部を有するモールド１２０を準備する工程と、充填ヘッドの吐出開口から、経皮吸収シート用の液状材料１７０を、モールドの段差部に囲まれた領域に供給する工程と、を有し、充填ヘッドは供給管路を画定する内壁面を有するヘッド本体１５２を備え、内壁面はヘッド本体の吐出開口に向けて漸次拡径するテーパ状管路を画定するテーパ状管路面１６０Ｂを含む。【選択図】図１０
