A compound represented by the formula (I), or a pharmacologically acceptable salt or solvate thereof: Het-X-Z (I) wherein, Het, represents a 1H-5-indazolyl or 5-isoquinolyl； X represents a group (iv) -N (-R1) -Q6-Q7-, where R1 represents a hydrogen atom； Q6, represents a saturated, five to seven membered carbocyclic group, or a saturated five to seven membered heterocyclic group, which contains a nitrogen atom and, the carbocyclic and heterocyclic groups, are optionally substituted by an atom of oxygen； and Q7, represents - (CH2) n1-CR2aR2b- (CH2) n2-, where, n1, is an integer that is 0 or 1, n2 is 0, R2a represents a hydrogen atom, and R2b represents an atom of hydrogen, C1-4 alkyl, or optionally substituted phenyl； - (CH2) p-NR3-, wherein, p is an integer that is 0 or 1, and R3, represents a hydrogen atom, C1-4 alkyl, or optionally substituted phenyl； or -NH- (CH2) q1-CR4aR4b- (CH2) q2 where, q1, is 0 or 1, q2 is 0, R4a represents a hydrogen atom, and R4b represents a hydrogen atom, C1-4 alkyl or phenyl optionally substituted and, Z, represents a hydrogen atom, a halogen atom, phenyl, cyclopropyl, cyclohexyl, furanyl, pyridyl, piperidyl, naphthyl, naphthalenyl, indenyl, indolyl, imidazolyl, thienyl, 1,3-benzodioxol, fluorenyl, or carbazolyl and, these groups, are optionally substituted.Un compuesto representado por la fórmula (I), o una sal o solvato de éste farmacológicamente aceptable: Het-X-Z (I) en donde, Het, representa un 1H-5-indazolilo ó 5-isoquinolilo； X, representa un grupo (iv) -N (-R1) -Q6-Q7-, en donde, R1, representa un átomo de hidrógeno； Q6, representa un grupo carbocíclico, saturado, de cinco a siete miembros, o un grupo heterocíclico, saturado, de cinco a siete miembros, que contiene un átomo de nitrógeno y, los grupos carbocíclicos y heterocíclicos, se encuentran opcionalmente sustituidos por un átomo de oxígeno； y Q7, representa - (CH2) n1-CR2aR2b- (CH2) n2-, en donde, n1, es un numero entero que es 0 ó 1, n2 es 0, R2a representa un átomo de hi
