7-substituted indirubin-3′oximes and their applications

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专利权人:

Laurent Meijer

发明人:

Laurent Meijer,Karima Bettayeb,Alexios-Le-Andros Skaltsounis,Prokopios Maglatis,Jacint Boix,Judit Ribas

申请号：

US12086984

公开号：

US08552053B2

申请日:

2006.12.21

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention relates to new 3′-, 7-substituted-indirubins of formula (I) wherein R represents N—OH, N—O-alkyl or N—O—CO-alkyl, NO—(Ra)n1-Het, N—O—(Y)n1—N Ra Rb, N—O—CO—N(Rb Rc), radical with Het representing an aliphatic nitrogeneous heterocycle, Y being an optionally substituted —CH2— radical, n1 being 1 to 3, and X is an halogen atom selected in the group comprising F, Cl, Br, I, and Z is H or CH3 and the salts thereof.

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