DRUGS MINERALS AND GENERICS ITALIA S.R.L. IN FORMA ABBREVIATA D.M.G. ITALIA S.R.L.
发明人:
MERCURI, Luigi
申请号：
IBIB2018/053514
公开号：
WO2018/215897A1
申请日:
2018.05.18
申请国别(地区):
IB
年份:
2018
代理人:
摘要：
The present invention relates to a liquid mixture or solid mixture, in powder or granules, comprising or, alternatively, consisting of alginic acid and hyaluronic acid, or a salt thereof, for use in the treatment, in particular in the curative treatment, of extraoesophageal symptoms or disorders caused or provoked by gastroesophageal reflux (GERD) or by a partial reflux of gastric contents, such as, for example, the partial upflow of pepsin, hydrochloric acid, gastric juices or acidic gastric vapours from the stomach and wherein said disorders or symptoms manifest themselves in an extraoesophageal region. The present invention further relates to a liquid composition or solid composition, in powder or granules, which comprises said liquid or solid mixture comprising or, alternatively, consisting of alginic acid and hyaluronic acid, or a salt thereof, and optionally pharmaceutical or food grade additives or excipients, for use in the treatment, in particular in the curative treatment, of extraoesophageal disorders or symptoms that manifest themselves in the extraoesophageal region represented by the eye or eyeball and/or periocular region in patients affected by gastroesophageal reflux (GERD) or by a partial reflux of gastric contents, such as, for example, the partial upflow of pepsin, hydrochloric acid, gastric juices or acidic gastric vapours from the stomach.La présente invention concerne un mélange liquide ou un mélange solide, en poudre ou en granulés, qui comprend en partie ou, alternativement, en totalité de l'acide alginique et de l'acide hyaluronique ou un sel de ceux-ci, qui est destiné à être utilisé dans le traitement, en particulier dans le traitement curatif, de symptômes ou de troubles extra-œsophagiens causés ou provoqués par un reflux gastro-œsophagien (RGO) ou par un reflux partiel de contenus gastriques, tel que par exemple une remontée partielle de pepsine, d'acide chlorhydrique, de sucs gastriques ou de vapeurs gastriques acides depuis l'estomac,
