The present invention is related to a compound of formula (I)(I) or a pharmaceutically acceptable salt or ester thereof. The present invention is further related to a method of healing and/or inhibiting formation of scar tissue in an external wound of a subject comprising topically administering to the external wound of the subject an effective amount of a compositing containing a compound that binds FK506 binding protein 4.本發明係關於具有結構式(I)(I)之一化合物或其一藥學上可接受鹽類或酯類。本發明更進一步係關於一種癒合與/或抑制一個體之一外部傷口中疤痕組織形成之方法,其包含對該個體之該外部傷口局部施予一有效量之組合物,其包含與FK506結合蛋白4相結合之一化合物。