Provided herein are methods for treating or preventing inflammation, or an inflammatory or autoimmune condition, methods for treating or preventing a skin or nail condition or infection, methods for treating or preventing symptoms of gastrointestinal infections, and methods for promoting wound healing. Embodiments of the methods comprise administering a combination of two or more strains of Lactobacillus selected from Lactobacillus buchneri, Lactobacillus zeae, Lacobacillus paracasei, Lactobacillus parafarraginis, and Lactobacillus rapi, and/or one or more culture supernatants or cell free filtrates derived from culture media in which one or more of said strains has been cultured.