Discloses the use of two or more strains of Lactobacillus selected from Lactobacillus parafarraginis, Lactobacillus buchneri, Lactobacillus rapi and Lactobacillus zeae, or culture supernatant or cell free filtrate derived from the culture supernatant for the treatment of microbial infections and associated diseases in therapeutic and non-therapeutic applications. Further biocontrol discloses compositions comprising the same.