Pigment Epithelium-Derived Factor (PEDF) and Peptide Derivatives Thereof for Use in Osteoblast Differentiation and Bone Growth

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专利权人:

Yale University

发明人:

Chung Chuhan

申请号：

US201515328147

公开号：

US2017216416(A1)

申请日:

2015.07.23

申请国别(地区):

美国

年份:

2017

代理人:

摘要：

The present invention provides compositions and methods for differentiating a stem cell into an osteoblast or osteoblast progenitor cell. In certain embodiments, the invention may be used for promoting bone formation and increasing bone mass. In one embodiment, the composition comprises an agent which increases PEDF expression, PEDF activity, or both. In one embodiment, the composition comprises full-length PEDF. In one embodiment, the composition comprises a PEDF fragment or PEDF-derived peptide.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/