MUTATED RICIN A CHAIN TOXINS WITH REDUCED TOXIC EFFECTS AND METHODS OF PRODUCTION THEREOF

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专利权人:

BOARD OF REGENTS; THE UNIVERSITY OF TEXAS SYSTEM

发明人:

申请号：

IL16826005

公开号：

IL168260A

申请日:

2005.04.27

申请国别(地区):

IL

年份:

2012

代理人:

摘要：

The present invention provides methods to produce immunotoxins (ITs) and cytokines with a reduced ability to promote vascular leak syndrome (VLS). The invention also provides ITs and cytokines which have been mutated to lack amino acid sequences which induce VLS.

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