Jari Helin,Juhani Saarinen,Tero Satomaa,Filip S. Ekholm
申请号:
US15320917
公开号:
US20180228906A1
申请日:
2015.06.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A molecule comprising a saccharide bound via an O-glycosidic bond to a hydroxyl group of a toxic payload molecule is disclosed. An antibody-drug conjugate comprising an antibody covalently bound to a toxic payload molecule, optionally via a linker group, and a saccharide bound via an O-glycosidic bond to a hydroxyl group of the toxic payload molecule is further disclosed.