Saccharide derivative of a toxic payload and antibody conjugates thereof

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专利权人:

Glykos Finland Oy

发明人:

Helin, Jari,Saarinen, Juhani,Satomaa, Tero,Ekholm, Filip S.

申请号：

AU2015282627

公开号：

AU2015282627A1

申请日:

2015.06.26

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

A molecule comprising a saccharide bound via an O- glycosidic bond to a hydroxyl group of a toxic payload molecule is disclosed. An antibody-drug conjugate comprising an antibody covalently bound to a toxic payload molecule, optionally via a linker group,and a saccharide bound via an O- glycosidic bond to a hydroxyl group of the toxic payload molecule is further disclosed.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/