TUMOR-SPECIFIC PAYLOAD DELIVERY AND IMMUNE ACTIVATION USING A HUMAN ANTIBODY TARGETING A HIGHLY SPECIFIC TUMOR CELL SURFACE ANTIGEN

• 收藏
• 分享

专利权人:

The Regents of the University of California

发明人:

Bin Liu,Scott Bidlingmaier,Yang Su

申请号：

US15779490

公开号：

US20180369409A1

申请日:

2016.11.29

申请国别(地区):

US

年份:

2018

代理人:

摘要：

This invention provides antibodies directed against a highly specific and previously unrecognized marker for cancerous cells. In certain embodiments an isolated antibody or fragment thereof that specifically binds human placentally expressed ALPP and/or ALPPL2, but not ALPL and ALPI that are expressed outside the placenta is provided as well as immunoconjugates comprising such antibodies.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/