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Viral replication inhibitors, their preparation process and their therapeutic uses
专利权人:
HIVIH
发明人:
BENAROUS, Richard,CHEVREUIL, Francis,LEDOUSSAL, Benoit,CHASSET, Sophie,LE STRAT, Frédéric
申请号:
ES13774453
公开号:
ES2641372T3
申请日:
2013.10.11
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Compound according to formula (I): ** Formula ** in which: * R1 and R6, identical or different, independently represent a hydrogen atom; - CN; -OH; -CF3; a halogen atom; a linear or branched C1-C3 alkyl or C1-C3 linear or branched heteroalkyl; * R2, unsubstituted or substituted by at least one T1, represents a partially or totally unsaturated or aromatic 5, 6 or 7-membered carbocycle; a partially, totally unsaturated or aromatic 5, 6 or 7-membered heterocycle; a partially or totally unsaturated or aromatic 5, 6 or 7 membered carbocycle fused with a saturated, partially or totally unsaturated or aromatic 5, 6 or 7 membered carbocycle; a partially or totally unsaturated or aromatic 5, 6 or 7 membered carbocycle fused with a saturated, partially or totally unsaturated or aromatic 5, 6 or 7 membered heterocycle; a partially or totally unsaturated or aromatic 5, 6 or 7-membered heterocycle condensed with a saturated, partially or totally unsaturated or aromatic 5, 6 or 7-membered carbocycle; a partially or totally unsaturated or aromatic 5, 6 or 7-membered heterocycle fused with a saturated, partially or totally unsaturated or aromatic 5, 6 or 7-membered heterocycle; * R3, unsubstituted or substituted by at least one T2, represents an aryl group; a condensed aryl with a saturated, partially or totally unsaturated or aromatic carbocycle of 5, 6 or 7 members; an aryl condensed with a saturated, partially or totally unsaturated or aromatic 5, 6 or 7-membered heterocycle; an aryl condensed with a saturated, partially or completely unsaturated or aromatic 4, 5, 6 or 7-membered heterocycle and also condensed with a saturated, partially or totally unsaturated or aromatic 4, 5, 6 or 7-membered heterocycle; a heteroaryl; a condensed heteroaryl with a saturated, partially or totally unsaturated or aromatic carbocycle of 5, 6 or 7 members; a heteroaryl fused to a saturated, partially or totally unsaturated or aromatic 5, 6 or 7-membered heterocycle; a C5-C7 cycloalkenyl; a C5-C7 cy
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