An endoscopic image pickup device includes a tubing, an image pickup module consisting of a lens and an image sensor and installed in one end of the tubing, a first light source installed in the same end of the tubing relative to the image pickup module and having an illumination range directly intersected with the image pickup range of the image pickup module, a second light source installed in the tubing and having an illumination range deviated from the illumination range of the first light source a predetermined angle and intersected with the illumination range of the first light source directly or indirectly, and a light source control means adapted for controlling on and/or off of said first light source and/or said second light source. Subject to the design that the illumination direction of the second light source is deviated from that of the first light source, the invention provides an extra illumination range, enhancing image clarity.