[Problem] To provide a composition for preventing and/or ameliorating cancer-related irreversible metabolism disorders. [Solution] The present inventors have made intensive studies. As a result, it is found that a composition comprising, as essential components, a whey protein hydrolysate, lecithin and an oil or fat containing oleic acid both of which have a lipid metabolism improving activity and palatinose which has an insulin saving effect has an effect of preventing and/or ameliorating cancer-related irreversible metabolism disorders. This finding leads to the accomplishment of the present invention. Specifically, in an in vivo test using a model transplanted with tumor cells, it is found that this composition has an effect of preventing and/or ameliorating the decrease in muscle mass and the like, which are symptoms of cancer-related irreversible metabolism disorders, without inhibiting the activities of an anti-cancer agent.本發明的目的是提供一種組合物,用於預防及其/或者改善癌症引起的非可逆性的代謝紊亂。本發明人潛心探討的結果,發現以乳清蛋白水解物、具備脂質代謝改善作用的卵磷脂、富含油酸的油脂、以及具備節約胰島素效果的帕拉金糖為基本成分的組合物,能夠預防以及/或者改善癌症引起的非可逆性的代謝紊亂,從而完成了本發明。具體地,發現在使用了移植了腫瘤細胞的大鼠in vivo(體內)試驗中,本發明的組合物,既不阻礙抗癌藥物的作用,同時能夠預防以及/或者改善肌肉含量降低等癌症引起的非可逆性的代謝紊亂的症狀。
