A drug reconstitution device, method of manufacturing the drug reconstitution device and method of producing a reconstituted drug solution using the drug reconstitution device utilizes a forward osmosis membrane element positioned within a housing of the device between an input chamber and an output chamber to draw liquid from the input chamber to the output chamber via an osmotic process. The output chamber contains draw solutes and a drug to be reconstituted to produce the reconstituted drug solution in the output chamber.