The Government of the U.S.A. as represented by the Secretary of the Department of Health and Human S;The UAB Research Foundation;Wake Forest University
发明人:
Mark T. Gladwin,Daniel B. Kim-Shapiro,Rakesh P. Patel,Jeffrey Kerby
申请号：
US15146190
公开号：
US20170087181A1
申请日:
2016.05.04
申请国别(地区):
US
年份:
2017
代理人:
摘要：
This disclosure relates to methods of using nitrite to detoxify stroma-free hemoglobin based blood substitutes. In particular, methods are described for using a blood substitute comprised of about equimolar amounts of nitrite and hemoglobin (e.g., nitrite-metHb) to treat, prevent, or ameliorate diseases of the blood in a subject, or as a blood replacement in a subject.
