A gelatin capsule composition that includes one or more first distinct regions comprising a gelatin and one or more second distinct regions comprising a water-insoluble rapid-release agent is provided.本文提供明膠膠囊組合物,其包括一或多個包含明膠之第一區隔區域及一或多個包含水不溶性快速釋放製劑之第二區隔區域。