A continuous process for making a multi-panel sterilization assembly, the process including the steps of: providing a moving, continuous base web providing a plurality of subassemblies applying the subassemblies in position on the moving, continuous base web to define repeating portions that incorporate the subassemblies and alternating portions that lack such subassemblies providing side tabs applying the side tabs in position on the moving, continuous base web with respect to at least one edge of the portions that incorporate the subassemblies attaching the subassemblies and the side tabs to the moving, continuous base web to form a continuous work-piece and separating the continuous work-piece into individual multi-panel sterilization assemblies, each multi-panel sterilization assembly comprising a barrier panel, a fold protection panel and at least one side tab, and collating multi-panel sterilization assemblies into a stack and folding the stack.