A medication dispensing device includes a medication bottle, a perfusion device, a filter and a dispensing needle. The dispensing needle includes a lower end being shrill, smooth and seamless and puncturing into the plug of the medication bottle. The dispensing needle includes a passageway therein, and includes an opening and a groove on the side wall of the dispensing needle. The dispensing needle can puncture into the plug of the medication bottle without creating any scraps stuck in the opening of the passageway or dropping into the medication bottle. The groove can release the air and pressure of the medication bottle when the pressure in the medication bottle increases during the injection of the medication solution. Accordingly, the smoothness of the dispensation of the medication solution is improved, and the contamination of the medication solution can be avoided.
