The immunity inhibiter and the anti- inflammation medicine are revealed effectively and at the same time the medicine which makes the revelation of the side effect decrease is offered. The medicine which becomes combining with diallyl sulfide or the diallyl ether compound and the immunity inhibiter and/or the anti- inflammation medicine which periphery possess the action which makes the lymphocyte decrease which circulates and possess 2- amino -1,3- propane diol structure.免疫抑制剤や抗炎症剤を効果的に発現し且つ副作用の発現を減少させる医薬を提供する。末梢を循環するリンパ球を減少させる作用を有し2-アミノ-1,3-プロパンジオール構造を有するジアリールスルフィド又はジアリールエーテル化合物と、免疫抑制剤及び/又は抗炎症剤とを組み合わせてなる医薬。