The present invention includes compositions and methods to reduce the inflammation in mammals. The present invention includes a group of mesenchymal stem cells with anti-inflammatory, anti-apoptotic, antitumor and immunomodulation.本発明は、哺乳類における炎症を減少させる方法及び組成を含む。本発明は、抗炎症性、抗アポトーシス、免疫調節及び抗腫瘍性を有する間葉幹細胞の一群を含む。