The invention relates to a use of an aurantiamide dipepetide derivative in the treatment or prevention of angiogenesis-related diseases. Accordingly, aurantiamide dipeptide derivatives can be used as angiogenesis inhibitor, whereby preventing or treating invasive and metastatic cancer and ocular neovascularization (particularly macular degeneration such as pathological neovascularization of age-related macular degeneration (AMD)).本發明係關於一種橙黃醯胺(aurantiamide)雙肽衍生物在治療或預防血管新生相關疾病之用途。因此,橙黃醯胺雙肽衍生物可以用作血管新生抑制劑,藉此預防或治療侵襲性及轉移性癌症及眼新血管生成(特別是黃斑變性,諸如年齡相關之黃斑變性(AMD)的病理性新血管生成)。
