Baxter, Ellen,Creighton, Christopher J.,Lu, Tianbao,Reitz, Allen B.,Reynolds, Charles H.,Morgan Ross, Tina,Sieber-McMaster, Ellen,Yung ho, Chih,Huang, Yifang,Luo, Chi
申请号:
AU2009209147
公开号:
AU2009209147B2
申请日:
2009.01.29
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention is directed to novel 2-amino-quinoline derivatives,pharmaceutical compositions containing them and their use in the treatmentof Alzheimer's disease (AD), mild cognitive impairment, senility and/ or dementia. The compounds of the present invention are inhibitors of β-secretase,also known as β-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.