Nitrogenous Heterocyclic Compounds, inhibitors of bace 1 or 2 of the bace； Pharmaceutical composition that comprises； Pharmaceutical Combination； its use in the Treatment or prevention of Alzheimer's disease and mild cognitive impairment.
SANGAMESH BADIGER,MURALI CHEBROLU,KONSTANZE HURTH,RAINER MARTIN LUEOEND,RAINER MACHAUER,HEINRICH RUEEGER,MARINA TINTELNOT-BLOMLEY,SIEM JACOB VEENSTRA,MARKUS VOEGTLE,SÉBASTIEN JACQUIER
申请号：
CL2014002518
公开号：
CL2014002518A1
申请日:
2014.09.23
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.<；p>；LA SOLICITUD SE REFIERE A UN PROCESO DE PREPARACIÓ；N DE COMPUESTOS DERIVADOS DE HETEROCICLOS NITROGENADOS, INHIBIDORES BACE-1 Y BACE-2<；/p>；
