A method for determining a spatially resolved distribution of a marker substance, a marker substance and a use of a marker substance in a quantitative magnetic resonance method is provided. To specify an effective possibility of determining a spatially resolved distribution of a marker substance in an object under examination, the method for determining a spatially resolved distribution of a marker substance, located in an object under examination, includes: acquiring magnetic resonance signals of an examination region of the object under examination by means of a quantitative magnetic resonance method, quantifying a measurement-n-tuple of material parameters with the aid of the acquired magnetic resonance signals, comparing the measurement-n-tuple with a known marker substance-n-tuple of the marker substance, calculating a spatially resolved distribution of the marker substance in the examination region with the aid of the result of the comparison, and providing the spatially resolved distribution of the marker substance.