The invention relates to granule formulations of 5-fluorocytosine (5-FC), and to their use for treating hyperproliferative diseases such as cancer and other disease, such as fungal diseases. The invention further relates to the manufacture of said granules.Linvention concerne des formulations granulaires de 5-fluorocytosine (5-FC) et leur utilisation pour le traitement de maladies dhyperprolifération, telles que le cancer ou une autre maladie, telle que des maladies fongiques. Linvention concerne en outre la fabrication desdits granules.