The present invention relates to a drug delivery agent form for treating a mental or central nervous system disease, more specifically, the present invention comprises a biodegradable polymer containing a microcapsule containing a drug and crosslinked hydrogel and a drug delivery agent form for treatment of central nervous system disease and The present invention relates to a method of manufacturing.The drug delivery agent form for treatment of psychiatric or central nervous system diseases according to the present invention isDrug infusion was gradually released at a constant rate without excessive release at the initial stageBecause the concentration of the blood drug can be maintained constant for a long timePrevent excessive initial release of drugs that were problematic during administration of conventional antipsychotic or antidepressant drugsNo need to be administered multiple times at regular intervalsThere is the advantage that it is possible to carry out the desired release behavior continuously in the single administration easily.In addition, the method of producing the compound of the compound carrier of the present invention is a simple process as compared with the conventional method, and it has the advantage that the manufacturing time and cost of the slow release type drug transfer agent form can be reduced.Diagram本発明は、精神疾患または中枢神経系疾患治療用薬物伝達剤形に関し、より具体的に、本発明は、生分解性高分子と薬物を含有するマイクロカプセルおよび架橋結合されたハイドロゲルを含む精神疾患または中枢神経系疾患治療用薬物伝達剤形およびこれを製造する方法に関する。本発明による精神疾患または中枢神経系疾患治療用薬物伝達剤形は、薬物注入初期の過度な放出なしに一定の速度で徐々に放出されて、血中薬物の濃度を長時間一定に維持することができるので、従来の抗精神病剤または抗うつ剤薬物の投与時に問題点であった薬物の過度な初期放出を防止し、一定の時間間隔で複数回投与する必要なく、単回投与で所望の放出挙動を持続的に容易に得ることができるという長所がある。また、本発明の悪物伝達剤形の製造方法は、従来の方法に比べて簡単な工程であって、徐放型薬物伝達剤形の製造時間と費用を節減することができるという長所がある。【選択図】図１
