Ajou University Industry-Academic Cooperation Foundation
发明人:
申请号:
EP18751180.3
公开号:
EP3581175A1
申请日:
2018.02.08
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to a drug delivery formulation for treating a mental illness or a central nervous system disorder and, more particularly, to a drug delivery formulation for treating a mental illness or a central nervous system disorder, comprising a microcapsule containing a biodegradable polymer and a drug and a crosslinked hydrogel and a method for preparing the same. A drug delivery formulation for treating a mental illness or a central nervous system disorder according to the present invention can slowly release a drug at a constant rate without a burst of drug release in the early stage of drug administration to maintain a constant blood drug level over a long period of time and thus enjoys the advantage of preventing excessive initial release of drug, which is a problem with the administration of conventional psychopharmaceutical agents or antidepressants, and easily obtaining a desirable sustained release behavior by single administration without necessity for multiple administrations divided at regular time intervals. In addition, a method for preparing a drug delivery formulation according to the present invention is a process simpler than conventional methods and has the advantage of reducing time and cost in preparing a sustained-release drug delivery formulation.