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Growth hormone secretatogue receptor antagonists and uses thereof
专利权人:
The Administrators of the Tulane Educational Fund;McGill University
发明人:
Bowers, Cyril Y.,Coy, David H.,Hocart, Simon J.,Tannenbaum, Gloria S.
申请号:
AU2011268256
公开号:
AU2011268256A1
申请日:
2011.06.16
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention provides novel peptides that can modulate the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and subtypes, isoforms and variants thereof). These peptides are useful as antagonists of the ghrelin receptor as well as inverse agonist, partial agonist or a combination of these activities as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, diabetes, central nervous system disorders, genetic disorders, and hyperproliferative disorders.
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