This Hair Ming Gong Open closes object containing controlling a effective amount of ledipasvir of Treatment and control a effective amount of sofosbuvir Drug Learn Group of Treatment, and wherein ledipasvir is substantially non-Jing Body, sofosbuvir is substantially Jing Body.本發明公開了含有治療有效量的ledipasvir和治療有效量的sofosbuvir的藥學組合物,其中ledipasvir基本上爲非晶體,sofosbuvir基本上爲晶體。