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Broadly neutralizing monoclonal antibodies against HIV-1 V1V2 Env region
专利权人:
The United States of America, as represented by the Secretary, Department of Health and Human SERVICES;Centre for the AIDS Programme of Rese;The Trustees of Columbia University in the City of New York
发明人:
Chaim Aryeh Schramm,Jason Gorman,John Mascola,Lawrence Stewart Shapiro,Lynn Morris,Nicole Amy Doria-Rose,Penelope Linda Moore,Peter Dak Pin Kwong,Salim Safurdeen Abdool Karim
申请号:
US15121051
公开号:
US10519222B2
申请日:
2015.02.27
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates anti-HIV therapies and prophylaxis. Specifically, the invention relates to broadly neutralizing antibodies against HIV-1, nucleic acids encoding these antibodies, vectors comprising the nucleic acids and cells and pharmaceutical compositions Comprising said vectors and/or antibodies. The present invention also relates to use of the antibodies and/or vectors for the treatment and/or prevention of HIV-1 infection in a subject. Furthermore, the invention also relates to a kit containing the antibodies of the invention.
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